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The tender-clipped sequences that overhang the breakpoint are collapsed into a consensus sequence using a several sequence alignment (MSA) delivered during the seqAn library [27]. Wham applies a few filters to the consensus sequences. Breakpoints usually are not noted in circumstances in which consensus sequences are shorter than 10 bp or contain m
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Wham clusters all the candidate breakpoints and rounds their positions to the closest tenth foundation pair. The situation with the highest go through support is described. When the smooth-clipped consensus sequence is often aligned for the putative breakpoint area using the Smith-Waterman algorithm, the breakpoint is even further refined to The si